Buy Imcivree Setmelanotide injection Online
Imcivree Setnelanotide Injection is a medicine used to treat obesity and help control hunger caused by certain genetic conditions that affect how
Imcivree is a medicine used to treat obesity and help control hunger caused by certain genetic conditions that affect how the brain controls feelings of hunger.
IMCIVREE is the first and only FDA-approved treatment to target an impaired MC4R pathway in the brain, a root cause of hunger and obesity in people living with Bardet-Biedl syndrome (BBS) or POMC, PCSK1, or LEPR deficiency
What is IMCIVREE?
IMCIVREE is a prescription medicine used in adults and children 6 years of age and older with obesity due to:
- The genetic conditions pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1 (PCSK1), or leptin receptor (LEPR) deficiency, to help them lose weight and keep the weight off
- Bardet-Biedl syndrome (BBS) to help them lose weight and keep the weight off
Your healthcare provider should order an FDA-approved test to confirm POMC, PCSK1, or LEPR deficiency before you start using IMCIVREE.
IMCIVREE is not for use in people with the following conditions because it may not work:
- Obesity due to suspected POMC, PCSK1, or LEPR deficiency not confirmed by genetic testing or with benign or likely benign genetic testing results
- Other types of obesity not related to POMC, PCSK1, or LEPR deficiency, or BBS, including obesity associated with other genetic conditions and general obesity
It is not known if IMCIVREE is safe and effective in children under 6 years of age.
Before you use IMCIVREE, tell your healthcare provider about all your medical conditions, including if you:
- Have or have had areas of darkened skin, including skin discoloration (hyperpigmentation)
- Have or have had depression, or suicidal thoughts or behavior
- Have kidney problems
- Are pregnant or planning to become pregnant. Losing weight while pregnant may harm your unborn baby. Your healthcare provider may stop your treatment with IMCIVREE if you become pregnant. Tell your healthcare provider if you become pregnant or think you might be pregnant during treatment with IMCIVREE
- Are breastfeeding or plan to breastfeed. It is not known if IMCIVREE passes into your breast milk. You should not breastfeed during treatment with IMCIVREE
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
See the detailed Instructions for Use that come with your IMCIVREE to learn how to prepare and inject IMCIVREE, and how to properly throw away (dispose of) used syringes and needles.
What are the possible side effects of IMCIVREE?
IMCIVREE may cause serious side effects, including:
- Male and female sexual function problems. IMCIVREE can cause an erection that happens without any sexual activity in males (spontaneous penile erection) and unwanted sexual reactions (changes in sexual arousal that happen without any sexual activity) in females. If you have an erection lasting longer than 4 hours, get emergency medical help right away
- Depression and suicidal thoughts or actions. You or a caregiver should call your healthcare provider right away if you have any new or worsening symptoms of depression, suicidal thoughts or behaviors, or any unusual changes in mood or behavior
- Increased skin pigmentation and darkening of skin lesions (moles or nevi) you already have. These changes happen because of how IMCIVREE works in the body and will go away when you stop using IMCIVREE. You should have a full body skin exam before starting and during treatment with IMCIVREE to check for skin changes
- Benzyl alcohol toxicity. Benzyl alcohol is a preservative in IMCIVREE. Benzyl alcohol can cause serious side effects, including death, in premature and low-birth weight infants who have received medicines that contain benzyl alcohol. IMCIVREE should not be used in premature and low-birth weight infants
The most common side effects of IMCIVREE include darkening of the skin, injection site reactions, nausea, headache, diarrhea, stomach pain, vomiting, depression, and an erection that happens without any sexual activity in males.
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Why is this medication prescribed?
Setmelanotide injection is used to lose weight and then to keep from gaining back that weight in certain adults and children 6 years of age or older who are obese due to certain inherited conditions including proopiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1 (PCSK1), or leptin receptor (LEPR) deficiency (inherited conditions that cause severe obesity) or Bardet-Biedl syndrome (BBS; an inherited condition that can cause severe obesity). Setmelanotide is in a class of medications called melanocortin 4 (MC4) receptor agonists. It works by activating pathways in the brain to promote weight loss by decreasing appetite and caloric intake, and increasing energy expenditure.
How should this medicine be used?
Setmelanotide comes as a solution (liquid) to inject subcutaneously (under the skin). It is usually injected once a day when you wake up with or without food. Use setmelanotide injection at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use setmelanotide injection exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.
Your doctor will probably start you on a low dose of setmelanotide and increase your dose after 2 weeks.
If you have POMC, PCSK1, or LEPR deficiency and you do not lose a certain amount of weight after 3 to 4 months of treatment with setmelanotide injection, it is not likely that you will benefit from using this medication. If you have Bardet-Biedl syndrome and you do not lose a certain amount of weight after 1 year of treatment with setmelanotide injection, it is not likely that you will benefit from using this medication. Your doctor may tell you to stop using setmelanotide injection.
You can inject setmelanotide injection yourself, or you can have a friend or relative inject the medication. Before you use setmelanotide injection for the first time, your doctor or nurse will show you how to prepare and inject a dose of the medication. Read the written instructions for use carefully before you inject the medication for the first time. Be sure to ask your doctor or pharmacist if you have any questions about how to inject the medication.
Before you are ready to inject setmelanotide injection, you will need to remove the medication from the refrigerator, and allow the vial to rest for 15 minutes so that it can warm to room temperature. Alternatively, you can warm the vial by gently rolling it between the palms of your hands for 60 seconds. Do not try to warm the medication by heating it in a microwave, placing it in hot water, or through any other method.
Always look at setmelanotide injection solution before injecting it. It should be clear and colorless to slightly yellow. Do not use setmelanotide injection if it is cloudy, contains particles, or if the expiration date marked on the vial has passed. Dispose of used syringes and needles in a puncture-resistant container. Talk to your doctor or pharmacist about how to dispose of the puncture-resistant container.
You can inject setmelanotide injection anywhere on the front of your thighs, the back of your upper arms, or your stomach except your navel and the area 2 inches (5 centimeters) around it. Do not inject the medications into an area where the skin is tender, bruised, red, or hard or where you have scars, moles, or stretch marks. Choose a different spot each time you inject the medication, at least 1 inch (2.5 centimeters) away from a spot that you have already used.
Setmelanotide injection needs to be continued regularly to maintain weight loss. Continue to use setmelanotide injection even if you feel well and are losing weight. Do not stop using setmelanotide injection without talking to your doctor.
Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
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